Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

Wain, L. V., Shrine, N., Miller, S., Jackson, V. E., Ntalla, I., Artigas, M. S., Billington, C. K., Kheirallah, A. K., Allen, R., Cook, J. P., Probert, K., Obeidat, M., Bossé, Y., Hao, K., Postma, D. S., Paré, P. D., Ramasamy, A., UK Brain Expression Consortium (UKBEC), Mägi, R., Mihailov, E., Reinmaa, E. and 20 moreWain, L. V., Shrine, N., Miller, S., Jackson, V. E., Ntalla, I., Artigas, M. S., Billington, C. K., Kheirallah, A. K., Allen, R., Cook, J. P., Probert, K., Obeidat, M., Bossé, Y., Hao, K., Postma, D. S., Paré, P. D., Ramasamy, A., UK Brain Expression Consortium (UKBEC), Mägi, R., Mihailov, E., Reinmaa, E., Melén, E., O’Connell, J., Frangou, E., Delaneau, O., OxGSK, C., Freeman, C., Petkova, D., McCarthy, M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I., Hansell, A. L., Thomson, N. C., Zeggini, E., Morris, A. P., Marchini, J., Strachan, D. P., Tobin, M. D., & Hall, I. P. (2015). Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. The Lancet Respiratory Medicine, 3(10), 769-781. doi:10.1016/S2213-2600(15)00283-0.
Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). We used UK Biobank data to study the genetic causes of smoking behaviour and lung health.
Publication type
Journal article
Publication date
2015

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