In my presentation I will discuss a series of ERP and imaging studies on sentence and discourse processing. The focus will be on both semantic and syntactic binding. A neurocomputational model of parsing will be proposed that accounts for both behavioral and ERP data on syntactic processing. A series of architectural principles of sentence and discourse processing will be discussed that are claimed to follow from the empirical data. Considerations of brain organization result in the proposal that the left prefrontal cortex is a crucial area for binding syntactic and semantic information that is retrieved from memory into a unified sentence/discourse level representation.